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替硝唑
貨號:T0893
產(chǎn)品名稱: 替硝唑
英文名: Tinidazole
CAS NO.: 19387-91-8
分子式: C8H13N3O4S
分子量: 247.271520376205
產(chǎn)品品牌: targetmol
產(chǎn)品規(guī)格: 25mg
替硝唑
替硝唑抑制劑Tinidazolea is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group, in turn, is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death.